Does Invisalign hurt?
It can, mostly at first. Invisalign is one brand of clear aligner. With aligners, as with braces, teeth may feel sore or under pressure for a few days after treatment starts. In studies, pain was usually worst in the first day or two and eased within about a week. Aligners are not painless, and they have not been shown to hurt less throughout treatment.
- Teeth may be sore in the first days, when they start to move; it tends to fade over about a week.
- Some studies found slightly less pain with aligners than with fixed braces in the first days; later findings were mixed.
- Over-the-counter painkillers reduced orthodontic pain in trials; anti-inflammatories and paracetamol were not shown to differ.
- Pain lasting more than a few days is a reason to contact your orthodontist.

Why teeth feel sore
Orthodontic treatment moves teeth by pressing on them gently and steadily. Clear aligners do this with a series of removable plastic trays, each shaped slightly differently from the last; fixed braces do it with brackets and a wire. The tissues around the roots respond to that pressure, and for a while the teeth can feel tender, tight or sensitive when you bite.
People describe it as an ache or pressure rather than a sharp pain. It is usually most noticeable when chewing. How much it bothers you varies from person to person, and this article cannot predict it for you. What it can do is tell you what the studies found, and how sure they are.
The first week
The NHS says teeth may be sore for a few days1 after braces are fitted, and suggests soft food and painkillers. Aligners behave in a similar way when treatment starts.
Most of the 12 studies in a review comparing aligners with fixed braces followed patients through the first week. In both groups, pain was usually highest in the first 24 to 48 hours and then gradually eased2, fading over about a week.
In these studies, the first two days were usually the worst, and the tenderness settled as the week went on.
Do aligners hurt less than braces?
A little, for a few days, in some studies. Not reliably after that. And the evidence is weaker than it sounds.
- The first days. A review of seven studies, all of one aligner brand and in adults with mild problems, found less pain with aligners than with fixed braces during the first few days3. After that, up to three months, no difference was found.
- Only on some days. The review of 12 studies found lower pain with aligners only on days 3 and 42, with no difference at 4 hours, 24 hours, day 2 or days 5 to 7.
- Later months. One study in that review followed patients every month for a year. From the second month on, patients with aligners reported more pain2 than those with fixed braces. It is a single study, but it shows that aligners do not always hurt less.
How certain is this? It depends on the review. The authors of the 12-study review rated the evidence on pain scores as very low. In the seven-study review, the non-randomised studies were rated low and its single randomised trial high. The seven-study review covered only one brand, in adults with mild problems, so its results may not apply to everyone.
Does each new set of aligners hurt?
People often ask whether each new set of trays brings the soreness back. The research does not tell us much about this. The reviews above measured pain mainly when treatment started, mostly over the first week; a few studies looked at later adjustments, but pain after each change of trays has not been studied systematically. Soreness may come back with a new set, but we cannot say how much or for how long.
The same goes for taking the trays out and putting them back in: we found no study that measured pain when removing aligners. If removing them hurts more than a little, ask your orthodontist to check the fit.
What helps with the soreness
Painkillers. A Cochrane review of 32 randomised trials found that over-the-counter painkillers reduced orthodontic pain compared with taking nothing or a placebo4, at 2, 6 and 24 hours (moderate-quality evidence). Anti-inflammatory painkillers (NSAIDs) and paracetamol were not shown to differ4 (low-quality evidence). Follow the leaflet, and ask a pharmacist or doctor if you are unsure which suits you.
Soft food. Aligners are taken out to eat. Eating soft food for the first days, as the NHS suggests1, makes chewing easier while the teeth are tender.
Things with little evidence. Another Cochrane review looked at non-drug methods. For chewing aids such as gum or bite wafers, and for vibration devices, the evidence was of very low quality and inconclusive5. For low-level laser it was of low quality, and the authors said they could not rely on the findings. Harms were not measured. These are not proven ways to reduce pain. No review we found tested aligner "chewies" for pain. With fixed braces, the NHS advises not to chew gum, because it can get stuck1.
Keep wearing the trays as prescribed. It can be tempting to leave them out when your teeth ache, but the treatment depends on wearing them for the hours your orthodontist sets.
When to contact your orthodontist or a dentist
Soreness in the first days is expected. Contact your orthodontist if:
- teeth are still painful more than a few days1 after starting or after an adjustment
- one tooth hurts much more than the others, or hurts on its own without pressure
- an edge of a tray cuts your gum, tongue or cheek, or a sore does not settle
- a tray no longer fits, cracks or is lost
Emergencies. Facial swelling, a fever or throbbing pain is not an expected part of orthodontic treatment: see a dentist without waiting. If you find it hard to breathe or swallow, or swelling spreads quickly in your mouth or neck, call 112 or go to the nearest emergency department.
Questions about aligner treatment?
Send us a message with your question. Our dentists will explain what an examination would look at and which options might be worth discussing.
Frequently asked questions
How long does Invisalign pain last?
In studies of orthodontic treatment, pain was usually worst in the first day or two and eased over about a week. If it is still painful after a few days, contact your orthodontist.
Does Invisalign hurt less than braces?
Some studies found slightly less pain with aligners in the first few days, but no difference later, and one study found more pain with aligners from the second month. The evidence is mostly low in certainty.
Does every new aligner hurt?
Soreness may come back with a new set, but pain after each change of trays has not been studied systematically, so we cannot say how much or for how long. Tell your orthodontist if a new set hurts a lot.
Which painkiller is best for aligner pain?
Trials found that ordinary over-the-counter painkillers reduce orthodontic pain; anti-inflammatory painkillers and paracetamol were not shown to differ. Follow the leaflet, and ask a pharmacist or doctor which suits you.
Do aligner chewies help with pain?
No review we found tested chewies for pain. For chewing gum and bite wafers, the evidence was of very low quality and inconclusive. Ask your orthodontist whether they want you to use chewies to seat the trays.
Sources
- Braces. NHS (UK). 2026.↩nhs.uk
- Comparison of pain intensity and impacts on oral health-related quality of life between orthodontic patients treated with clear aligners and fixed appliances: a systematic review and meta-analysis. BMC Oral Health 2023;23(1):920. 2023.↩doi.org
- Pain level between clear aligners and fixed appliances: a systematic review. Progress in Orthodontics 2020;21(1):3. 2020.↩doi.org
- Pharmacological interventions for pain relief during orthodontic treatment. Cochrane Database of Systematic Reviews 2017;11:CD003976. 2017.↩doi.org
- Non-pharmacological interventions for alleviating pain during orthodontic treatment. Cochrane Database of Systematic Reviews 2016;12:CD010263. 2016.↩doi.org

Dt. Dilek AKSU GÜLER
Dentist · Founder
She has completed advanced training in implantology and works in aesthetic restorations and smile design.